Frequently Asked Questions

Naturally, our families have many questions and concerns. Often, they are about to start an unfamiliar procedure with little known terminology. Most likely, you never anticipated needing such a procedure. Our goal is to help you build a healthy family. To help us reach that goal, Genesis Genetics welcomes your questions. We are happy to work with you in an effort to minimize your concerns.

When starting this process, many families have similar questions. We have listed these below. Feel free to review the list. If your concerns are not addressed here, please contact one of our genetic counsellors.

How do we know Genesis Genetics will be able to help us if you haven’t performed PGD for my specific mutation?

Our geneticists are world-renowned for their expertise in designing the necessary probes for testing a number of the most complicated mutations. Discuss your mutation with one of our genetic counselors to learn more about the specific steps that PGD encompasses. Count on us to thoroughly explain how our laboratory will help you. In the UK only HFEA licensed conditions can be performed by PGD. Currently there are approximately 230 licensed conditions HFEA PGD licensed conditions Outside the UK Genesis Genetics have run many more conditions what we test for Genesis Genetics USA and where appropriate we can, with your IVF clinic, apply for a license for your condition.

How long will this process take?

The molecular DNA testing of a single cell is a complicated process. Each test is custom designed specifically for each family at Genesis Genetics. There is a significant amount of preliminary work that is required prior to you actually starting the IVF process. This scientific work varies with the type of disease, the family’s genetic mutations and the steps involved in customizing and optimizing the “molecular spell checkers.” The process of building your customized probe usually takes 12 weeks using standard PGD . However Karyomapping (ultraPGD in the USA) can be used to build a test in less than 4 weeks.

Are costs for PGD included in our IVF fees?

As with any medical procedure, issues exist when you decide to use in vitro fertilization (IVF) and PGD to help you have a healthy baby. We know you are making important emotional, psychological and final decisions. In advance of starting IVF, you should meet with the social and financial consultants at your reproductive clinic. The PGD laboratories at Genesis Genetics are not involved with these IVF discussions or fees. Regardless, we want you to be happy with the entire process.

There are many factors that enter into the costs quoted to you: your geographic location, if you have had problems getting pregnant, the type and amount of hormone medication, micro manipulation costs (ICSI, embryo biopsy) and whether the NHS  covers all/some of the process. Prior to beginning any medical procedures Genesis Genetics joins with your reproductive center to fully inform you about these costs. These fees are discussed in detail with you during a conference call.

How often is PGD used? Is it only used in a worse-case scenario or can it be used as a preventive measure as well?

Genesis Genetics believes that PGD should be used for only the most serious inherited diseases. We will only perform HFEA licensed conditions and only apply for licenses for the most serious inherited diseases.

Will the biopsy hurt the embryo or cause any damage to our baby?

It is not unusual for our families to be concerned about the harmful effects a biopsy might have on the embryo. During the last decade, studies have shown that the developing fetus is not harmed a result of an embryo biopsy. Performing a biopsy on the embryo is crucial to the reliability of PGD. By using the biopsied cell(s) for PGD testing, we are able to analyze as much of the genetic code as necessary in order to determine if the mutation exists in that specific embryo. Performing biopsy on the day 5 embryo trophectoderm (which goes on to form the placenta not the embryo) takes 3-5cells and since this performs in a superior manner for Karyomapping this biopsy type, compared to a day3 biopsy, is recommend Karyomapping PGD

Dictionary of PGD/ PGS terminology

PGD/PGS terminology

About Us

Genesis Genetics is the pioneer of preimplantation testing of embryos for inherited genetic abnormalities, and was founded by world renowned scientists largely responsible for discovering preimplantation genetic diagnosis (PGD) as a clinical practice and performed the first successful cases in the world.


Contact Genesis Genetics

London Biosciences Innovation Centre
London NW1 0NH
Phone: +44 (0)20 7691 2084
Email: ggeulab1@genesisgenetics.org
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